Stadium: Tullio Field Round: 1
| NCAAF | 2022/11/05 18:00 | Seton Hill Griffins v Mercyhurst | L | 7-0 |
| NCAAF | 2021/10/09 16:00 | Mercyhurst v Seton Hill Griffins | L | 17-19 |
| NCAAF | 2019/10/19 16:00 | Mercyhurst v Seton Hill Griffins | L | 20-30 |
| NCAAF | 2018/10/13 16:00 | Seton Hill Griffins v Mercyhurst | L | 34-33 |