Matías Knudsen (born 5 October 1999) is a Colombian professional squash player. He reached a career high ranking of 62 in the world during June 2025.
Knudsen, who attended Drexel University, where he earned a master's degree in business administration, won the 2023 Colleyville Open. He has also represented Colombia in international competitions. He was named as Philadelphia's 2023 performer of the year.
In 2024, Knudsen won his 4th PSA title after securing victory in the Club Campestre de Medellín during the 2024–25 PSA Squash TourWorld Championship Qualifiers. In April 2025 he won a 5th PSA title after winning the World Championship Qualifiers and added a sixth after winning the República Dominicana Open.