| NCAAF | 11/15 18:00 | 1 | Millikin Big Blue v Elmhurst Bluejays | W | 29-22 | |
| NCAAF | 11/08 18:00 | 1 | Wheaton Thunder v Millikin Big Blue | L | 61-14 | |
| NCAAF | 11/01 18:00 | 1 | Millikin Big Blue v Washington Bears | L | 7-38 | |
| NCAAF | 10/25 18:00 | 1 | Carthage Red Men v Millikin Big Blue | L | 24-7 | |
| NCAAF | 10/18 15:30 | 1 | Millikin Big Blue v Illinois Wesleyan Titans | L | 27-49 | |
| NCAAF | 10/11 23:00 | 1 | North Central Illinois v Millikin Big Blue | L | 59-10 | |
| NCAAF | 10/04 18:00 | 1 | Millikin Big Blue v Carroll Pioneers | L | 17-28 | |
| NCAAF | 09/27 18:00 | 1 | Augustana Augie v Millikin Big Blue | L | 33-6 | |
| NCAAF | 09/20 23:00 | 1 | Millikin Big Blue v Cayre/Furness | W | 22-17 | |
| NCAAF | 09/06 18:00 | 1 | Luther Norse v Millikin Big Blue | W | 3-33 | |
| NCAAF | 11/16 19:00 | 1 | Elmhurst Bluejays v Millikin Big Blue | L | 35-7 | |
| NCAAF | 11/09 19:00 | 1 | Millikin Big Blue v Wheaton Thunder | L | 10-64 | |
| NCAAF | 11/02 17:00 | 1 | Washington Bears v Millikin Big Blue | L | 70-21 | |
| NCAAF | 10/26 18:00 | 1 | Millikin Big Blue v Carthage Red Men | L | 20-24 | |
| NCAAF | 10/19 18:00 | 1 | Illinois Wesleyan Titans v Millikin Big Blue | L | 51-8 | |
| NCAAF | 10/12 18:00 | 1 | Millikin Big Blue v North Central Illinois | L | 14-70 | |
| NCAAF | 10/05 19:00 | 1 | Carroll Pioneers v Millikin Big Blue | L | 49-14 | |
| NCAAF | 09/28 18:00 | 1 | Millikin Big Blue v Augustana Augie | L | 20-24 | |
| NCAAF | 09/21 18:00 | 1 | North Park Vikings v Millikin Big Blue | L | 44-0 | |
| NCAAF | 09/07 18:00 | 1 | Millikin Big Blue v Illinois College Blueboys | L | 21-46 | |
| NCAAF | 11/11 19:00 | 1 | Millikin Big Blue v Carthage Red Men | L | 15-24 | |
| NCAAF | 11/04 18:00 | 1 | Carroll Pioneers v Millikin Big Blue | L | 41-0 | |
| NCAAF | 10/28 18:00 | 1 | Millikin Big Blue v Wheaton Thunder | L | 0-75 | |
| NCAAF | 10/21 18:00 | 1 | Elmhurst Bluejays v Millikin Big Blue | L | 29-27 | |
| NCAAF | 10/14 18:00 | 1 | Millikin Big Blue v North Central Illinois | L | 3-75 | |
| NCAAF | 10/07 18:00 | 1 | Augustana Augie v Millikin Big Blue | L | 42-3 | |
| NCAAF | 09/30 18:00 | 1 | Millikin Big Blue v Illinois Wesleyan Titans | L | 17-45 | |
| NCAAF | 09/23 18:00 | 1 | North Park Vikings v Millikin Big Blue | L | 38-0 | |
| NCAAF | 09/16 18:00 | 1 | Millikin Big Blue v Washington Bears | L | 13-63 | |
| NCAAF | 09/02 23:00 | 1 | Kwai Tsing DFA v Millikin Big Blue | L | 31-0 |