Stadium: Wintrust Arena
Home Manager: Jim Flanery Away Manager: Doug Bruno
| WNCAAB | 2022/02/27 17:00 | DePaul (W) v Creighton (W) | L | 90-84 |
| WNCAAB | 2022/02/05 01:00 | Creighton (W) v DePaul (W) | W | 77-68 |
| WNCAAB | 2021/02/20 19:00 | Creighton (W) v DePaul (W) | W | 83-72 |
| WNCAAB | 2020/12/23 02:00 | DePaul (W) v Creighton (W) | L | 90-81 |
| WNCAAB | 2020/02/01 01:00 | Creighton (W) v DePaul (W) | W | 63-61 |
| WNCAAB | 2020/01/05 19:00 | Creighton (W) v DePaul (W) | L | 71-74 |
| WNCAAB | 2019/03/11 22:30 | Creighton (W) v DePaul (W) | L | 69-80 |
| WNCAAB | 2019/03/03 19:00 | DePaul (W) v Creighton (W) | L | 74-67 |
| WNCAAB | 2022/03/27 23:00 | Creighton (W) v South Carolina (W) | L | 50-80 |
| WNCAAB | 2022/03/26 01:30 | Creighton (W) v Iowa State (W) | W | 76-68 |
| WNCAAB | 2022/03/20 17:00 | Creighton (W) v Iowa (W) | W | 64-62 |
| WNCAAB | 2022/03/18 17:30 | Creighton (W) v Colorado (W) | W | 84-74 |
| WNCAAB | 2022/03/06 02:30 | Creighton (W) v Seton Hall (W) | L | 65-66 |
| WNCAAB | 2022/02/27 17:00 | DePaul (W) v Creighton (W) | L | 90-84 |
| WNCAAB | 2022/02/20 18:00 | Creighton (W) v Seton Hall (W) | W | 97-91 |
| WNCAAB | 2022/02/18 18:00 | Creighton (W) v St. John's (W) | W | 107-59 |
| WNCAAB | 2022/03/17 01:00 | DePaul (W) v Dayton Women | L | 57-88 |
| WNCAAB | 2022/03/05 19:30 | Marquette (W) v DePaul (W) | L | 105-85 |
| WNCAAB | 2022/02/27 17:00 | DePaul (W) v Creighton (W) | W | 90-84 |
| WNCAAB | 2022/02/26 01:00 | Seton Hall (W) v DePaul (W) | L | 94-90 |
| WNCAAB | 2022/02/20 19:00 | DePaul (W) v Villanova Women | L | 64-73 |
| WNCAAB | 2022/02/17 01:00 | Marquette (W) v DePaul (W) | W | 66-77 |
| WNCAAB | 2022/02/13 19:00 | DePaul (W) v Georgetown (W) | W | 105-104 |
| WNCAAB | 2022/02/12 00:00 | DePaul (W) v Connecticut (W) | L | 60-84 |