Stadium: The Buc Dome
Home Manager: Barclay Radebaugh Away Manager: Quinton Ferrell
| NCAAB | 2022/02/24 00:00 | Charleston Southern v Presbyterian | W | 48-68 |
| NCAAB | 2022/01/27 00:00 | Presbyterian v Charleston Southern | W | 62-61 |
| NCAAB | 2021/02/22 23:00 | Charleston Southern v Presbyterian | L | 78-77 |
| NCAAB | 2020/03/04 00:00 | Presbyterian v Charleston Southern | L | 64-81 |
| NCAAB | 2020/02/29 21:00 | Charleston Southern v Presbyterian | W | 65-76 |
| NCAAB | 2020/01/24 00:30 | Presbyterian v Charleston Southern | L | 66-74 |
| NCAAB | 2019/03/02 21:00 | Charleston Southern v Presbyterian | L | 72-65 |
| NCAAB | 2019/01/31 00:30 | Presbyterian v Charleston Southern | L | 84-85 |
| NCAAB | 2022/03/03 01:30 | Presbyterian v Campbell | L | 72-75 |
| NCAAB | 2022/02/26 21:30 | Presbyterian v UNC Asheville | L | 96-98 |
| NCAAB | 2022/02/24 00:00 | Charleston Southern v Presbyterian | W | 48-68 |
| NCAAB | 2022/02/19 21:00 | Gardner Webb v Presbyterian | L | 76-68 |
| NCAAB | 2022/02/16 23:00 | Presbyterian v USC Upstate | L | 55-60 |
| NCAAB | 2022/02/12 21:30 | Presbyterian v Winthrop | L | 61-65 |
| NCAAB | 2022/02/10 00:00 | High Point v Presbyterian | L | 79-70 |
| NCAAB | 2022/02/08 00:00 | Presbyterian v Hampton | L | 69-74 |
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | L | 62-72 |
| NCAAB | 2022/03/02 19:00 | Charleston Southern v UNC Asheville | W | 79-78 |
| NCAAB | 2022/02/26 21:00 | Charleston Southern v Winthrop | L | 86-92 |
| NCAAB | 2022/02/24 00:00 | Charleston Southern v Presbyterian | L | 48-68 |
| NCAAB | 2022/02/19 22:30 | USC Upstate v Charleston Southern | L | 78-73 |
| NCAAB | 2022/02/17 00:00 | UNC Asheville v Charleston Southern | L | 85-66 |
| NCAAB | 2022/02/12 19:00 | Charleston Southern v Gardner Webb | L | 65-82 |
| NCAAB | 2022/02/10 00:00 | Charleston Southern v North Carolina A&T | L | 51-62 |