Stadium: Banterra Center
Home Manager: Darian DeVries Away Manager: Bryan Mullins
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | W | 52-65 |
| NCAAB | 2022/02/26 21:00 | Southern Illinois v Drake | W | 60-62 |
| NCAAB | 2022/01/18 01:00 | Drake v Southern Illinois | W | 60-59 |
| NCAAB | 2021/01/05 00:00 | Southern Illinois v Drake | W | 55-86 |
| NCAAB | 2021/01/03 23:00 | Southern Illinois v Drake | W | 55-73 |
| NCAAB | 2020/02/01 23:00 | Southern Illinois v Drake | L | 79-72 |
| NCAAB | 2020/01/19 21:00 | Drake v Southern Illinois | L | 49-66 |
| NCAAB | 2019/02/13 01:00 | Drake v Southern Illinois | W | 72-69 |
| NCAAB | 2022/11/10 01:00 | IU Indianapolis v Drake | W | 48-80 |
| CBI | 2022/03/21 17:00 | Drake v UNC Wilmington | L | 75-76 |
| CBI | 2022/03/19 16:00 | IPFW v Drake | W | 65-87 |
| NCAAB | 2022/03/06 19:00 | Loyola Chicago v Drake | L | 64-58 |
| NCAAB | 2022/03/05 23:00 | Drake v Missouri State | W | 79-78 |
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | W | 52-65 |
| NCAAB | 2022/02/26 21:00 | Southern Illinois v Drake | W | 60-62 |
| NCAAB | 2022/02/24 00:00 | Drake v Valparaiso | W | 71-65 |
| NCAAB | 2022/11/11 01:00 | Southern Illinois v Oklahoma State | W | 61-60 |
| NCAAB | 2022/11/08 01:00 | Arkansas LR v Southern Illinois | W | 63-94 |
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | L | 52-65 |
| NCAAB | 2022/02/26 21:00 | Southern Illinois v Drake | L | 60-62 |
| NCAAB | 2022/02/24 01:00 | Illinois St v Southern Illinois | W | 69-90 |
| NCAAB | 2022/02/19 18:00 | Southern Illinois v Indiana State | W | 76-72 |
| NCAAB | 2022/02/16 01:00 | Bradley v Southern Illinois | W | 57-65 |
| NCAAB | 2022/02/13 01:00 | Evansville v Southern Illinois | W | 62-69 |