Stadium: F. G. Clark Center
Home Manager: Donte' Jackson Away Manager: Sean Woods
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | W | 60-58 |
| NCAAB | 2022/02/19 22:30 | Grambling State v Southern | W | 61-57 |
| NCAAB | 2022/01/15 23:00 | Southern v Grambling State | W | 77-83 |
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | W | 67-72 |
| NCAAB | 2021/02/07 01:00 | Grambling State v Southern | W | 72-69 |
| NCAAB | 2021/01/09 23:30 | Southern v Grambling State | L | 61-55 |
| NCAAB | 2020/02/08 23:30 | Southern v Grambling State | W | 62-66 |
| NCAAB | 2020/01/11 23:30 | Grambling State v Southern | W | 61-56 |
| NCAAB | 2022/03/11 20:00 | Grambling State v Texas Southern | L | 54-73 |
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | W | 60-58 |
| NCAAB | 2022/03/05 22:30 | Grambling State v Alabama State | L | 75-78 |
| NCAAB | 2022/03/04 01:30 | Grambling State v Alabama A&M | L | 63-71 |
| NCAAB | 2022/03/01 01:30 | Bethune Cookman v Grambling State | L | 69-63 |
| NCAAB | 2022/02/26 20:30 | Florida A&M v Grambling State | L | 79-73 |
| NCAAB | 2022/02/19 22:30 | Grambling State v Southern | W | 61-57 |
| NCAAB | 2022/02/15 01:30 | Grambling State v Prairie View | L | 70-71 |
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | L | 60-58 |
| NCAAB | 2022/03/05 22:00 | Southern v Alabama A&M | W | 50-49 |
| NCAAB | 2022/03/04 02:00 | Southern v Alabama State | L | 67-77 |
| NCAAB | 2022/03/01 02:00 | Florida A&M v Southern | W | 49-58 |
| NCAAB | 2022/02/26 23:30 | Bethune Cookman v Southern | L | 87-84 |
| NCAAB | 2022/02/19 22:30 | Grambling State v Southern | L | 61-57 |
| NCAAB | 2022/02/15 01:30 | Southern v Texas Southern | W | 70-58 |
| NCAAB | 2022/02/12 23:30 | Southern v Prairie View | L | 77-84 |