Stadium: F. G. Clark Center
Home Manager: Donte' Jackson Away Manager: Sean Woods
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | W | 60-58 |
| NCAAB | 2022/02/19 22:30 | Grambling State v Southern | W | 61-57 |
| NCAAB | 2022/01/15 23:00 | Southern v Grambling State | W | 77-83 |
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | W | 67-72 |
| NCAAB | 2021/02/07 01:00 | Grambling State v Southern | W | 72-69 |
| NCAAB | 2021/01/09 23:30 | Southern v Grambling State | L | 61-55 |
| NCAAB | 2020/02/08 23:30 | Southern v Grambling State | W | 62-66 |
| NCAAB | 2020/01/11 23:30 | Grambling State v Southern | W | 61-56 |
| NCAAB | 2022/11/12 01:00 | Colorado v Grambling State | W | 74-83 |
| NCAAB | 2022/11/08 01:00 | Grambling State v UNT Dallas | W | 82-57 |
| NCAAB | 2022/03/11 20:00 | Grambling State v Texas Southern | L | 54-73 |
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | W | 60-58 |
| NCAAB | 2022/03/05 22:30 | Grambling State v Alabama State | L | 75-78 |
| NCAAB | 2022/03/04 01:30 | Grambling State v Alabama A&M | L | 63-71 |
| NCAAB | 2022/03/01 01:30 | Bethune Cookman v Grambling State | L | 69-63 |
| NCAAB | 2022/02/26 20:30 | Florida A&M v Grambling State | L | 79-73 |
| NCAAB | 2022/11/12 02:00 | Southern v Arizona | L | 78-95 |
| NCAAB | 2022/11/08 03:15 | Southern v UNLV | L | 56-66 |
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | L | 60-58 |
| NCAAB | 2022/03/05 22:00 | Southern v Alabama A&M | W | 50-49 |
| NCAAB | 2022/03/04 02:00 | Southern v Alabama State | L | 67-77 |
| NCAAB | 2022/03/01 02:00 | Florida A&M v Southern | W | 49-58 |
| NCAAB | 2022/02/26 23:30 | Bethune Cookman v Southern | L | 87-84 |
| NCAAB | 2022/02/19 22:30 | Grambling State v Southern | L | 61-57 |