Stadium: Welsh-Ryan Arena
Home Manager: Chris Collins Away Manager: Byron Smith
| NCAAB | 2022/03/10 02:30 | Prairie View v Alcorn State | L | 63-64 |
| NCAAB | 2022/03/06 01:30 | Prairie View v Texas Southern | L | 77-78 |
| NCAAB | 2022/03/01 02:00 | Jackson State v Prairie View | L | 59-53 |
| NCAAB | 2022/02/26 23:30 | Alcorn State v Prairie View | L | 72-69 |
| NCAAB | 2022/02/22 01:30 | Prairie View v Mississippi Valley State | W | 69-64 |
| NCAAB | 2022/02/19 23:30 | Prairie View v Arkansas-Pine Bluff | W | 92-84 |
| NCAAB | 2022/02/15 01:30 | Grambling State v Prairie View | W | 70-71 |
| NCAAB | 2022/02/12 23:30 | Southern v Prairie View | W | 77-84 |
| NCAAB | 2022/03/10 19:00 | Northwestern v Iowa | L | 76-112 |
| NCAAB | 2022/03/09 23:00 | Nebraska v Northwestern | W | 69-71 |
| NCAAB | 2022/03/07 00:30 | Minnesota v Northwestern | W | 62-75 |
| NCAAB | 2022/03/01 01:00 | Northwestern v Iowa | L | 61-82 |
| NCAAB | 2022/02/26 00:00 | Northwestern v Penn State | L | 60-67 |
| NCAAB | 2022/02/23 01:00 | Nebraska v Northwestern | W | 65-77 |
| NCAAB | 2022/02/19 21:00 | Northwestern v Minnesota | L | 60-77 |
| NCAAB | 2022/02/17 02:00 | Purdue v Northwestern | L | 70-64 |