Head to Head
| Uruguay Apertura | 2022/04/03 00:00 | Defensor Sporting v CA River Plate | W | 3-2 |
| Uruguay Clausura | 2021/02/01 00:30 | Defensor Sporting v CA River Plate | L | 0-2 |
| Uruguay Torneo Intermedio | 2020/11/29 20:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Apertura | 2020/03/08 20:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Clausura | 2019/11/16 19:00 | CA River Plate v Defensor Sporting | L | 1-0 |
| Uruguay Torneo Intermedio | 2019/07/27 18:00 | CA River Plate v Defensor Sporting | L | 2-1 |
| Uruguay Apertura | 2019/05/11 18:30 | Defensor Sporting v CA River Plate | D | 1-1 |
| Uruguay Clausura | 2018/09/23 19:00 | CA River Plate v Defensor Sporting | L | 3-2 |
Home History
| Uruguay Torneo Intermedio | 2022/06/19 23:00 | Cerrito v Defensor Sporting | W | 1-2 |
| Uruguay Torneo Intermedio | 2022/06/13 22:30 | Defensor Sporting v Nacional De Football | L | 0-1 |
| Uruguay Apertura | 2022/06/05 15:00 | Rentistas v Defensor Sporting | L | 1-0 |
| Uruguay Apertura | 2022/05/29 20:30 | Defensor Sporting v Deportivo Maldonado | D | 1-1 |
| Uruguay Apertura | 2022/05/22 18:30 | Danubio v Defensor Sporting | W | 1-2 |
| Uruguay Apertura | 2022/05/14 21:00 | Defensor Sporting v Nacional De Football | L | 0-2 |
| Uruguay Apertura | 2022/05/07 16:00 | Albion FC v Defensor Sporting | W | 0-3 |
| Uruguay Apertura | 2022/04/25 23:00 | Defensor Sporting v Cerrito | D | 0-0 |
Away History
| Uruguay Torneo Intermedio | 2022/06/18 21:00 | Nacional De Football v CA River Plate | L | 3-0 |
| Uruguay Torneo Intermedio | 2022/06/10 18:00 | CA River Plate v Cerrito | W | 3-0 |
| Uruguay Apertura | 2022/06/03 22:15 | Torque v CA River Plate | D | 0-0 |
| Uruguay Apertura | 2022/05/29 18:00 | CA River Plate v Penarol | D | 0-0 |
| Copa Sudamericana | 2022/05/26 22:15 | Racing Club v CA River Plate | W | 0-1 |
| Uruguay Apertura | 2022/05/22 16:00 | Liverpool Montevideo v CA River Plate | L | 2-1 |
| Copa Sudamericana | 2022/05/18 22:15 | CA River Plate v Cuiaba | L | 1-2 |
| Uruguay Apertura | 2022/05/13 18:00 | CA River Plate v Rentistas | W | 1-0 |
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