Stadium: Strawberry Stadium Round: 1
Home Manager: G.J. Kinne Away Manager: Frank Scelfo
| NCAAF | 2021/11/06 19:00 | SE Louisiana v Incarnate Word | W | 52-55 |
| NCAAF | 2021/03/20 19:00 | SE Louisiana v Incarnate Word | W | 45-56 |
| NCAAF | 2019/10/12 21:00 | Incarnate Word v SE Louisiana | W | 27-21 |
| NCAAF | 2018/10/06 21:00 | SE Louisiana v Incarnate Word | W | 34-52 |
| NCAAF | 2017/10/07 15:00 | SE Louisiana v Incarnate Word | L | 49-30 |
| NCAAF | 2021/12/04 20:00 | Incarnate Word v Sam Houston State | L | 42-49 |
| NCAAF | 2021/11/27 20:00 | Stephen F. Austin v Incarnate Word | W | 28-35 |
| NCAAF | 2021/11/20 20:00 | Incarnate Word v Houston Christian | W | 55-14 |
| NCAAF | 2021/11/13 21:00 | Incarnate Word v Nicholls State | W | 27-23 |
| NCAAF | 2021/11/06 19:00 | SE Louisiana v Incarnate Word | W | 52-55 |
| NCAAF | 2021/10/30 20:00 | Houston Christian v Incarnate Word | W | 21-49 |
| NCAAF | 2021/10/23 17:00 | Incarnate Word v McNeese State | L | 20-28 |
| NCAAF | 2021/10/16 16:00 | Nicholls State v Incarnate Word | W | 21-38 |
| NCAAF | 2021/12/04 19:00 | SE Louisiana v James Madison | L | 20-59 |
| NCAAF | 2021/11/28 00:00 | Florida A&M v SE Louisiana | W | 14-38 |
| NCAAF | 2021/11/19 00:00 | Nicholls State v SE Louisiana | L | 45-42 |
| NCAAF | 2021/11/14 00:00 | Northwestern State v SE Louisiana | W | 28-56 |
| NCAAF | 2021/11/06 19:00 | SE Louisiana v Incarnate Word | L | 52-55 |
| NCAAF | 2021/10/30 23:00 | McNeese State v SE Louisiana | W | 20-23 |
| NCAAF | 2021/10/23 20:00 | SE Louisiana v Northwestern State | W | 51-14 |
| NCAAF | 2021/10/16 21:00 | Houston Christian v SE Louisiana | W | 24-61 |