| Nicaragua Liga de Ascenso | 2021/10/10 21:00 | San Marcos FC v Genesis Rivas | L | 2-0 |
| Nicaragua Segunda Division | 2021/03/24 21:00 | Genesis Rivas v San Marcos FC | L | 0-2 |
| Nicaragua Segunda Division | 2021/12/06 21:00 | Genesis Rivas v CS Municipal | W | 1-0 |
| Nicaragua Segunda Division | 2021/12/04 20:26 | Genesis Rivas v CS Municipal | D | 0-0 |
| Nicaragua Liga de Ascenso | 2021/10/10 21:00 | San Marcos FC v Genesis Rivas | L | 2-0 |
| Nicaragua Segunda Division | 2021/10/10 14:00 | Deportivo Masaya v Genesis Rivas | D | 2-2 |
| Nicaragua Segunda Division | 2021/03/28 21:00 | Masachapa FC v Genesis Rivas | L | 2-0 |
| Nicaragua Segunda Division | 2021/03/24 21:00 | Genesis Rivas v San Marcos FC | L | 0-2 |
| Nicaragua Segunda Division | 2021/03/21 21:00 | Deportivo Masaya v Genesis Rivas | L | 12-0 |
| Nicaragua Segunda Division | 2021/03/13 21:00 | Real Granada FC v Genesis Rivas | W | 1-3 |
| Nicaragua Liga de Ascenso | 2021/10/10 21:00 | San Marcos FC v Genesis Rivas | W | 2-0 |
| Nicaragua Liga de Ascenso | 2021/09/05 21:00 | San Marcos FC v Sapoa FC Cardenas | W | 4-1 |
| Nicaragua Segunda Division | 2021/08/29 14:00 | Deportivo Masaya v San Marcos FC | L | 2-1 |
| Nicaragua Cup | 2021/08/05 02:00 | CD Walter Ferretti v San Marcos FC | L | 10-0 |
| Nicaragua Segunda Division | 2021/05/09 16:00 | Matagalpa FC v San Marcos FC | L | 4-1 |
| Nicaragua Segunda Division | 2021/05/02 21:00 | UNAN Managua v San Marcos FC | L | 3-2 |
| Nicaragua Segunda Division | 2021/04/28 21:00 | San Marcos FC v UNAN Managua | W | 2-1 |
| Nicaragua Segunda Division | 2021/04/21 21:00 | San Marcos FC v Real Granada FC | D | 2-2 |