Stadium: Orleans Arena Round: 3
Home Manager: Molly Goodenbour Away Manager: Bill Carr
| WNCAAB | 2022/01/18 01:00 | San Francisco (W) v Santa Clara (W) | W | 67-60 |
| WNCAAB | 2022/01/16 01:00 | San Francisco (W) v Santa Clara (W) | L | 78-83 |
| WNCAAB | 2021/02/20 22:00 | San Francisco (W) v Santa Clara (W) | W | 87-64 |
| WNCAAB | 2021/01/24 03:00 | Santa Clara (W) v San Francisco (W) | W | 54-67 |
| WNCAAB | 2020/03/05 20:00 | San Francisco (W) v Santa Clara (W) | L | 65-72 |
| WNCAAB | 2020/02/01 22:00 | Santa Clara (W) v San Francisco (W) | W | 66-72 |
| WNCAAB | 2020/01/04 22:00 | San Francisco (W) v Santa Clara (W) | L | 72-80 |
| WNCAAB | 2019/02/02 22:00 | Santa Clara (W) v San Francisco (W) | W | 49-57 |
| WNCAAB | 2022/02/25 03:00 | San Francisco (W) v Loyola Marymount (W) | W | 74-67 |
| WNCAAB | 2022/02/19 22:00 | San Francisco (W) v Pepperdine (W) | W | 74-66 |
| WNCAAB | 2022/02/18 02:00 | Portland (W) v San Francisco (W) | W | 72-80 |
| WNCAAB | 2022/02/12 22:00 | Gonzaga (W) v San Francisco (W) | L | 83-82 |
| WNCAAB | 2022/02/11 03:00 | San Francisco (W) v Pacific Women | W | 77-70 |
| WNCAAB | 2022/02/08 02:00 | San Francisco (W) v Gonzaga (W) | L | 49-55 |
| WNCAAB | 2022/02/05 22:00 | Pepperdine (W) v San Francisco (W) | W | 57-78 |
| WNCAAB | 2022/02/04 02:00 | San Diego (W) v San Francisco (W) | W | 48-61 |
| WNCAAB | 2022/02/25 02:00 | BYU (W) v Santa Clara (W) | L | 103-66 |
| WNCAAB | 2022/02/21 22:00 | Santa Clara (W) v Gonzaga (W) | L | 58-74 |
| WNCAAB | 2022/02/19 22:00 | Portland (W) v Santa Clara (W) | W | 66-76 |
| WNCAAB | 2022/02/18 03:00 | Santa Clara (W) v Pepperdine (W) | W | 63-54 |
| WNCAAB | 2022/02/12 22:00 | Santa Clara (W) v Loyola Marymount (W) | W | 62-61 |
| WNCAAB | 2022/02/11 02:00 | Gonzaga (W) v Santa Clara (W) | L | 72-55 |
| WNCAAB | 2022/02/08 02:00 | Saint Mary's (W) v Santa Clara (W) | L | 88-81 |
| WNCAAB | 2022/02/05 22:00 | San Diego (W) v Santa Clara (W) | W | 84-89 |