Stadium: Jenny Craig Pavilion
Home Manager: Sam Scholl Away Manager: Herb Sendek
| NCAAB | 2021/02/19 02:00 | San Diego v Santa Clara | L | 71-60 |
| NCAAB | 2021/01/17 22:00 | Santa Clara v San Diego | W | 69-63 |
| NCAAB | 2020/01/25 23:00 | Santa Clara v San Diego | W | 65-52 |
| NCAAB | 2020/01/04 22:00 | San Diego v Santa Clara | W | 63-80 |
| NCAAB | 2019/03/09 04:20 | San Diego v Santa Clara | L | 62-45 |
| NCAAB | 2019/01/04 03:00 | San Diego v Santa Clara | W | 56-68 |
| NCAAB | 2018/02/10 21:00 | San Diego v Santa Clara | W | 64-70 |
| NCAAB | 2018/01/26 03:00 | Santa Clara v San Diego | L | 58-66 |
| NCAAB | 2021/11/23 03:30 | TCU v Santa Clara | W | 66-85 |
| NCAAB | 2021/11/20 02:00 | Cal Poly SLO v Santa Clara | W | 57-87 |
| NCAAB | 2021/11/17 02:00 | Nevada v Santa Clara | W | 74-96 |
| NCAAB | 2021/11/13 04:00 | Stanford v Santa Clara | W | 72-88 |
| NCAAB | 2021/11/10 02:00 | CS Fullerton v Santa Clara | W | 77-84 |
| NCAAB | 2021/03/07 05:00 | Santa Clara v Pepperdine | L | 70-78 |
| NCAAB | 2021/03/06 05:00 | Santa Clara v Pacific | W | 81-76 |
| NCAAB | 2021/03/05 05:00 | Portland v Santa Clara | W | 86-95 |
| NCAAB | 2021/11/20 03:00 | CS Fullerton v San Diego | L | 57-55 |
| NCAAB | 2021/11/18 03:30 | Cal Riverside v San Diego | W | 62-74 |
| NCAAB | 2021/11/16 02:00 | San Diego v California | L | 70-75 |
| NCAAB | 2021/11/13 03:00 | San Diego v Nevada | W | 75-68 |
| NCAAB | 2021/11/10 03:30 | San Diego v La Verne | W | 103-38 |
| NCAAB | 2021/03/05 02:00 | San Diego v San Francisco | L | 51-67 |
| NCAAB | 2021/02/27 21:00 | Pepperdine v San Diego | L | 90-84 |
| NCAAB | 2021/02/23 20:00 | Pacific v San Diego | L | 77-67 |