Stadium: D.J. Sokol Arena
Home Manager: Doug Bruno Away Manager: Jim Flanery
| WNCAAB | 2021/02/20 19:00 | Creighton (W) v DePaul (W) | L | 83-72 |
| WNCAAB | 2020/12/23 02:00 | DePaul (W) v Creighton (W) | W | 90-81 |
| WNCAAB | 2020/02/01 01:00 | Creighton (W) v DePaul (W) | L | 63-61 |
| WNCAAB | 2020/01/05 19:00 | Creighton (W) v DePaul (W) | W | 71-74 |
| WNCAAB | 2019/03/11 22:30 | Creighton (W) v DePaul (W) | W | 69-80 |
| WNCAAB | 2019/03/03 19:00 | DePaul (W) v Creighton (W) | W | 74-67 |
| WNCAAB | 2018/12/30 01:00 | Creighton (W) v DePaul (W) | L | 85-82 |
| WNCAAB | 2018/02/03 01:00 | Creighton (W) v DePaul (W) | W | 67-77 |
| WNCAAB | 2021/03/20 19:00 | DePaul (W) v Drake (W) | L | 91-100 |
| WNCAAB | 2021/03/19 22:00 | St Louis Women v DePaul (W) | L | 74-72 |
| WNCAAB | 2021/03/06 20:00 | Villanova Women v DePaul (W) | L | 78-72 |
| WNCAAB | 2021/03/01 22:00 | Butler (W) v DePaul (W) | L | 86-81 |
| WNCAAB | 2021/02/27 18:00 | Providence (W) v DePaul (W) | W | 49-75 |
| WNCAAB | 2021/02/24 22:00 | Marquette (W) v DePaul (W) | L | 85-71 |
| WNCAAB | 2021/02/20 19:00 | Creighton (W) v DePaul (W) | L | 83-72 |
| WNCAAB | 2021/02/17 22:00 | Xavier (W) v DePaul (W) | W | 75-83 |
| WNCAAB | 2021/03/20 22:00 | Northern Iowa (W) v Creighton (W) | L | 64-63 |
| WNCAAB | 2021/03/19 19:00 | Creighton (W) v Bowling Green (W) | W | 72-65 |
| WNCAAB | 2021/03/07 23:00 | Creighton (W) v Marquette (W) | L | 59-64 |
| WNCAAB | 2021/03/07 02:00 | Creighton (W) v Seton Hall (W) | W | 83-76 |
| WNCAAB | 2021/03/05 22:00 | Georgetown (W) v Creighton (W) | W | 42-56 |
| WNCAAB | 2021/02/25 22:00 | Connecticut (W) v Creighton (W) | L | 81-49 |
| WNCAAB | 2021/02/23 00:00 | Creighton (W) v Marquette (W) | L | 41-65 |
| WNCAAB | 2021/02/20 19:00 | Creighton (W) v DePaul (W) | W | 83-72 |