Stadium: Littlejohn Coliseum
Home Manager: Darrick Gibbs Away Manager: Amanda Butler
| WNCAAB | 2021/03/13 00:00 | North Florida (W) v Liberty (W) | L | 52-65 |
| WNCAAB | 2021/03/12 00:00 | North Alabama (W) v North Florida (W) | W | 74-86 |
| WNCAAB | 2021/03/06 22:00 | North Florida (W) v Bellarmine (W) | W | 77-49 |
| WNCAAB | 2021/03/06 00:00 | North Florida (W) v Bellarmine (W) | W | 76-73 |
| WNCAAB | 2021/02/28 19:00 | North Florida (W) v Florida Gulf Coast (W) | L | 54-66 |
| WNCAAB | 2021/02/27 19:00 | Florida Gulf Coast (W) v North Florida (W) | L | 94-45 |
| WNCAAB | 2021/02/21 19:00 | North Florida (W) v Lipscomb Women | L | 70-74 |
| WNCAAB | 2021/02/20 19:00 | North Florida (W) v Lipscomb Women | W | 74-57 |
| WNCAAB | 2021/03/20 21:00 | Delaware (W) v Clemson (W) | L | 87-74 |
| WNCAAB | 2021/03/19 18:00 | Ohio (W) v Clemson (W) | W | 60-65 |
| WNCAAB | 2021/03/06 01:30 | Clemson (W) v Georgia Tech (W) | L | 57-60 |
| WNCAAB | 2021/03/05 01:30 | Clemson (W) v Notre Dame (W) | W | 68-63 |
| WNCAAB | 2021/02/28 19:00 | Miami Florida (W) v Clemson (W) | L | 68-62 |
| WNCAAB | 2021/02/25 23:00 | Virginia Tech (W) v Clemson (W) | L | 70-64 |
| WNCAAB | 2021/02/19 00:00 | North Carolina (W) v Clemson (W) | L | 77-64 |
| WNCAAB | 2021/02/14 17:00 | Wake Forest Women v Clemson (W) | L | 72-65 |