Stadium: Cintas Center
Home Manager: Geno Auriemma Away Manager: Melanie Moore
| WNCAAB | 2021/02/20 20:00 | Connecticut (W) v Xavier (W) | W | 83-32 |
| WNCAAB | 2020/12/19 18:00 | Xavier (W) v Connecticut (W) | W | 59-106 |
| WNCAAB | 2021/12/19 20:30 | Louisville (W) v Connecticut (W) | L | 69-64 |
| WNCAAB | 2021/12/11 18:00 | UCLA (W) v Connecticut (W) | W | 61-71 |
| WNCAAB | 2021/12/10 00:00 | Connecticut (W) v Georgia Tech (W) | L | 44-57 |
| WNCAAB | 2021/12/05 17:00 | Notre Dame (W) v Connecticut (W) | W | 54-73 |
| WNCAAB | 2021/12/04 00:00 | Connecticut (W) v Seton Hall (W) | W | 74-49 |
| WNCAAB | 2021/11/22 17:00 | South Carolina (W) v Connecticut (W) | L | 73-57 |
| WNCAAB | 2021/11/21 17:00 | Connecticut (W) v South Florida (W) | W | 60-53 |
| WNCAAB | 2021/11/20 17:00 | Connecticut (W) v Minnesota (W) | W | 88-58 |
| WNCAAB | 2022/01/02 19:00 | Creighton (W) v Xavier (W) | L | 67-51 |
| WNCAAB | 2021/12/29 19:00 | Butler (W) v Xavier (W) | W | 55-77 |
| WNCAAB | 2021/12/19 19:00 | SE Missouri State (W) v Xavier (W) | W | 58-65 |
| WNCAAB | 2021/12/12 19:00 | Xavier (W) v Cincinnati (W) | L | 73-82 |
| WNCAAB | 2021/12/08 17:00 | Niagara (W) v Xavier (W) | W | 78-82 |
| WNCAAB | 2021/12/05 23:00 | Xavier (W) v DePaul (W) | L | 85-103 |
| WNCAAB | 2021/12/04 01:00 | Xavier (W) v Marquette (W) | L | 48-76 |
| WNCAAB | 2021/11/27 19:00 | Xavier (W) v Eastern Kentucky (W) | W | 73-60 |