[2] TOR Maple Leafs 5-4 BUF Sabres [5] 2021-10-14 14:00
Stadium: KeyBank Center
Home Manager: Sheldon Keefe Away Manager: Don Granato
Head to Head
| NHL | 2020/02/17 00:00 | TOR Maple Leafs v BUF Sabres | L | 2-5 |
| NHL | 2019/12/18 00:00 | BUF Sabres v TOR Maple Leafs | W | 3-5 |
| NHL | 2019/12/01 00:00 | BUF Sabres v TOR Maple Leafs | W | 1-2 |
| NHL | 2019/11/29 21:00 | TOR Maple Leafs v BUF Sabres | L | 4-6 |
| NHL Pre-Season | 2019/09/21 23:00 | TOR Maple Leafs v BUF Sabres | L | 3-5 |
| NHL Pre-Season | 2019/09/20 23:00 | BUF Sabres v TOR Maple Leafs | W | 0-3 |
| NHL | 2019/03/20 23:00 | TOR Maple Leafs v BUF Sabres | W | 4-2 |
| NHL | 2019/03/03 00:00 | BUF Sabres v TOR Maple Leafs | W | 2-5 |
Home History
| NHL | 2021/10/13 23:00 | MTL Canadiens v TOR Maple Leafs | W | 1-2 |
| NHL Pre-Season | 2021/10/09 23:00 | OTT Senators v TOR Maple Leafs | W | 1-4 |
| NHL Pre-Season | 2021/10/05 23:00 | MTL Canadiens v TOR Maple Leafs | W | 2-6 |
| NHL Pre-Season | 2021/10/04 23:00 | TOR Maple Leafs v OTT Senators | W | 3-1 |
| NHL Pre-Season | 2021/09/29 23:00 | TOR Maple Leafs v OTT Senators | W | 4-0 |
| NHL Pre-Season | 2021/09/27 23:00 | TOR Maple Leafs v MTL Canadiens | L | 2-5 |
| NHL Pre-Season | 2021/09/25 23:00 | MTL Canadiens v TOR Maple Leafs | W | 1-4 |
| NHL | 2021/05/31 23:00 | MTL Canadiens v TOR Maple Leafs | L | 3-1 |
Away History
| NHL Pre-Season | 2021/10/09 19:00 | DET Red Wings v BUF Sabres | W | 1-3 |
| NHL Pre-Season | 2021/10/05 23:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2021/10/04 23:00 | CLB Blue Jackets v BUF Sabres | L | 5-3 |
| NHL Pre-Season | 2021/10/01 23:00 | PIT Penguins v BUF Sabres | L | 2-1 |
| NHL Pre-Season | 2021/09/30 23:30 | BUF Sabres v DET Red Wings | L | 2-6 |
| NHL Pre-Season | 2021/09/28 23:00 | BUF Sabres v CLB Blue Jackets | W | 5-4 |
| NHL | 2021/05/08 19:00 | BUF Sabres v PIT Penguins | L | 0-1 |
| NHL | 2021/05/06 23:00 | BUF Sabres v PIT Penguins | L | 4-8 |
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