Stadium: Jan Breydel Stadium Round: 26
Referee: Nicolas Laforge Home Manager: Alfred Schreuder Away Manager: Hein van Haezebrouck
| Belgium First Division A | 2021/08/29 11:30 | Gent v Club Brugge | L | 6-1 |
| Belgium First Division A | 2021/03/15 19:45 | Gent v Club Brugge | W | 0-4 |
| Belgium First Division A | 2020/12/20 12:30 | Club Brugge v Gent | L | 0-1 |
| Club Friendly List | 2020/07/18 16:00 | Club Brugge v Gent | L | 2-3 |
| Belgium First Division A | 2019/12/22 13:30 | Gent v Club Brugge | D | 1-1 |
| Belgium First Division A | 2019/10/06 12:30 | Club Brugge v Gent | W | 4-0 |
| Belgium First Division A | 2019/05/05 16:00 | Gent v Club Brugge | W | 0-1 |
| Belgium First Division A | 2019/03/31 16:00 | Club Brugge v Gent | W | 3-0 |
| Belgium First Division A | 2021/12/15 20:00 | OH Leuven v Club Brugge | W | 1-4 |
| Belgium First Division A | 2021/12/12 20:00 | Club Brugge v Zulte-Waregem | W | 3-0 |
| UEFA Champions League | 2021/12/07 17:45 | PSG v Club Brugge | L | 4-1 |
| Belgium First Division A | 2021/12/04 19:45 | Club Brugge v Seraing United | W | 3-2 |
| Belgium Cup | 2021/12/01 19:45 | Genk v Club Brugge | D | 3-3 |
| Belgium First Division A | 2021/11/28 12:30 | Genk v Club Brugge | W | 2-3 |
| UEFA Champions League | 2021/11/24 20:00 | Club Brugge v RB Leipzig | L | 0-5 |
| Belgium First Division A | 2021/11/19 19:45 | KV Mechelen v Club Brugge | L | 2-1 |
| Belgium First Division A | 2021/12/15 17:45 | KV Mechelen v Gent | L | 4-3 |
| Belgium First Division A | 2021/12/12 17:30 | Gent v Genk | W | 1-0 |
| UEFA Conference League | 2021/12/09 17:45 | Gent v FC Flora Tallinn | W | 1-0 |
| Belgium First Division A | 2021/12/04 15:15 | OH Leuven v Gent | W | 0-1 |
| Belgium Cup | 2021/12/01 19:00 | Lommel v Gent | W | 0-2 |
| Belgium First Division A | 2021/11/28 17:30 | Gent v Standard Liege | W | 3-1 |
| UEFA Conference League | 2021/11/25 20:00 | Anorthosis Famagusta v Gent | L | 1-0 |
| Belgium First Division A | 2021/11/20 17:30 | Zulte-Waregem v Gent | W | 1-2 |