Head to Head
| Mexico Liga MX Femenil | 2019/09/24 00:00 | Leon (W) v Santos Laguna (W) | L | 2-0 |
| Mexico Liga MX Femenil | 2019/04/02 03:00 | Leon (W) v Santos Laguna (W) | L | 1-0 |
| Mexico Liga MX Femenil | 2019/02/05 01:00 | Santos Laguna (W) v Leon (W) | L | 0-1 |
| Mexico Liga MX Femenil | 2018/10/26 00:00 | Leon (W) v Santos Laguna (W) | L | 3-0 |
| Mexico Liga MX Femenil | 2018/08/21 02:00 | Santos Laguna (W) v Leon (W) | L | 1-2 |
| Mexico Liga MX Femenil | 2018/03/20 03:00 | Santos Laguna (W) v Leon (W) | W | 4-2 |
| Mexico Liga MX Femenil | 2018/01/26 16:00 | Leon (W) v Santos Laguna (W) | W | 0-1 |
Home History
| Mexico Liga MX Femenil | 2020/01/20 21:45 | Club America (W) v Santos Laguna (W) | L | 3-2 |
| Mexico Liga MX Femenil | 2020/01/14 03:00 | Santos Laguna (W) v Necaxa (W) | D | 2-2 |
| Mexico Liga MX Femenil | 2020/01/07 02:00 | Atletico San Luis (W) v Santos Laguna (W) | L | 3-1 |
| Mexico Liga MX Femenil | 2019/11/12 01:00 | Toluca (W) v Santos Laguna (W) | L | 2-0 |
| Mexico Liga MX Femenil | 2019/11/05 01:00 | Santos Laguna (W) v Mazatlan FC (W) | L | 1-2 |
| Mexico Liga MX Femenil | 2019/10/28 22:00 | Necaxa (W) v Santos Laguna (W) | L | 1-0 |
| Mexico Liga MX Femenil | 2019/10/24 23:00 | Santos Laguna (W) v Atletico San Luis (W) | D | 1-1 |
| Mexico Liga MX Femenil | 2019/10/22 00:00 | Santos Laguna (W) v Club America (W) | L | 0-1 |
Away History
| Mexico Liga MX Femenil | 2020/01/21 01:00 | Chivas Guadalajara (W) v Leon (W) | L | 4-3 |
| Mexico Liga MX Femenil | 2020/01/14 01:00 | Leon (W) v Tigres UANL (W) | L | 0-1 |
| Mexico Liga MX Femenil | 2020/01/07 01:00 | Pachuca (W) v Leon (W) | L | 3-1 |
| Mexico Liga MX Femenil | 2019/11/08 18:00 | Atlas (W) v Leon (W) | W | 1-3 |
| Mexico Liga MX Femenil | 2019/11/05 01:00 | Leon (W) v Puebla (W) | D | 3-3 |
| Mexico Liga MX Femenil | 2019/10/29 01:00 | Leon (W) v Tijuana (W) | W | 2-0 |
| Mexico Liga MX Femenil | 2019/10/24 23:00 | Tigres UANL (W) v Leon (W) | L | 1-0 |
| Mexico Liga MX Femenil | 2019/10/19 16:00 | Unam Pumas (W) v Leon (W) | L | 1-0 |
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