Stadium: Knapp Center
Home Manager: Scott Nagy Away Manager: Eric Henderson
| NCAAB | 2025/03/07 18:00 | Southern Illinois v Drake | L | 53-70 |
| NCAAB | 2025/02/01 19:00 | Drake v Southern Illinois | L | 75-65 |
| NCAAB | 2024/02/08 01:00 | Southern Illinois v Drake | L | 88-92 |
| NCAAB | 2024/01/14 01:00 | Drake v Southern Illinois | L | 76-58 |
| NCAAB | 2023/03/04 23:00 | Southern Illinois v Drake | L | 52-65 |
| NCAAB | 2023/02/11 19:00 | Southern Illinois v Drake | L | 59-82 |
| NCAAB | 2023/01/05 01:00 | Drake v Southern Illinois | W | 49-53 |
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | L | 52-65 |
| NCAAB | 2025/12/21 19:00 | Southern Illinois v Bradley | L | 69-73 |
| NCAAB | 2025/12/19 02:00 | Illinois St v Southern Illinois | L | 75-68 |
| NCAAB | 2025/12/13 23:00 | Southern Illinois v Richmond | L | 84-93 |
| NCAAB | 2025/12/11 01:00 | Tennessee Martin v Southern Illinois | W | 54-83 |
| NCAAB | 2025/12/04 00:00 | Southern Illinois v High Point | W | 86-84 |
| NCAAB | 2025/11/30 00:00 | Arkansas LR v Southern Illinois | W | 65-74 |
| NCAAB | 2025/11/27 01:00 | Southern Illinois v Memphis | L | 58-74 |
| NCAAB | 2025/11/24 18:30 | Southern Illinois v UAB | L | 73-81 |
| NCAAB | 2025/12/21 21:00 | Drake v Evansville | W | 66-65 |
| NCAAB | 2025/12/19 01:00 | Drake v Murray State | L | 72-81 |
| NCAAB | 2025/12/13 19:00 | North Dakota State v Drake | L | 99-94 |
| NCAAB | 2025/12/06 00:30 | UAB v Drake | L | 74-69 |
| NCAAB | 2025/12/03 00:30 | Western Illinois v Drake | W | 57-108 |
| NCAAB | 2025/11/29 21:00 | Georgia Tech v Drake | W | 74-84 |
| NCAAB | 2025/11/29 02:30 | Drake v LSU | L | 62-71 |
| NCAAB | 2025/11/22 00:30 | Drake v Buena Vista | W | 98-52 |