Stadium: Jack Breslin Students Events Center Round: 1
Home Manager: Chris Collins Away Manager: Tom Izzo
| NCAAB | 2018/02/17 19:00 | Michigan State v Northwestern | L | 65-60 |
| NCAAB | 2016/12/30 23:00 | Northwestern v Michigan State | L | 52-61 |
| NCAAB | 2016/01/29 02:00 | Northwestern v Michigan State | L | 45-76 |
| NCAAB | 2015/02/11 00:00 | Northwestern v Michigan State | L | 44-68 |
| NCAAB | 2015/01/11 17:00 | Michigan State v Northwestern | L | 84-77 |
| NCAAB | 2014/03/14 12:00 | Michigan State v Northwestern | L | 67-51 |
| NCAAB | 2012/01/14 12:00 | Northwestern v Michigan State | W | 81-74 |
| NCAAB | 2011/01/15 12:00 | Michigan State v Northwestern | L | 71-67 |
| NCAAB | 2018/11/17 00:00 | Binghamton v Northwestern | W | 54-82 |
| NCAAB | 2018/11/13 01:00 | American v Northwestern | W | 51-63 |
| NCAAB | 2018/11/09 01:00 | New Orleans v Northwestern | W | 52-82 |
| NCAAB | 2018/03/01 23:30 | Northwestern v Penn State | L | 57-65 |
| NCAAB | 2018/02/26 00:30 | Northwestern v Iowa | L | 70-77 |
| NCAAB | 2018/02/23 00:00 | Wisconsin v Northwestern | L | 70-64 |
| NCAAB | 2018/02/20 00:00 | Maryland v Northwestern | L | 71-64 |
| NCAAB | 2018/02/17 19:00 | Michigan State v Northwestern | L | 65-60 |
| NCAAB | 2018/11/18 23:00 | Tennessee Tech v Michigan State | W | 33-101 |
| NCAAB | 2018/11/15 00:00 | UL Monroe v Michigan State | W | 59-80 |
| NCAAB | 2018/11/11 23:00 | Florida Gulf Coast v Michigan State | W | 82-106 |
| NCAAB | 2018/11/07 00:00 | Michigan State v Kansas | L | 87-92 |
| NCAAB | 2018/03/18 18:40 | Syracuse v Michigan State | L | 55-53 |
| NCAAB | 2018/03/16 23:10 | Bucknell v Michigan State | W | 78-82 |
| NCAAB | 2018/03/03 19:00 | Michigan v Michigan State | L | 75-64 |
| NCAAB | 2018/03/02 17:00 | Wisconsin v Michigan State | W | 60-63 |