Stadium: Colonial Life Arena
Home Manager: Semeka Randall Lay Away Manager: Dawn Staley
| WNCAAB | 2025/03/08 23:00 | High Point (W) v Winthrop (W) | L | 64-49 |
| WNCAAB | 2025/03/06 19:00 | Charleston Southern (W) v Winthrop (W) | W | 45-48 |
| WNCAAB | 2025/03/01 19:00 | UNC Asheville Women v Winthrop (W) | W | 66-71 |
| WNCAAB | 2025/02/26 22:30 | Longwood (W) v Winthrop (W) | L | 59-55 |
| WNCAAB | 2025/02/19 23:00 | Winthrop (W) v Presbyterian (W) | W | 60-55 |
| WNCAAB | 2025/02/16 00:00 | Winthrop (W) v High Point (W) | L | 56-69 |
| WNCAAB | 2025/02/13 00:00 | Radford (W) v Winthrop (W) | W | 68-78 |
| WNCAAB | 2025/02/08 19:00 | Winthrop (W) v USC Upstate (W) | L | 48-52 |
| WNCAAB | 2025/04/06 19:00 | Connecticut (W) v South Carolina (W) | L | 82-59 |
| WNCAAB | 2025/04/04 23:00 | Texas (W) v South Carolina (W) | W | 57-74 |
| WNCAAB | 2025/03/30 17:00 | Duke (W) v South Carolina (W) | W | 50-54 |
| WNCAAB | 2025/03/28 21:00 | Maryland (W) v South Carolina (W) | W | 67-71 |
| WNCAAB | 2025/03/23 19:00 | Indiana (W) v South Carolina (W) | W | 53-64 |
| WNCAAB | 2025/03/21 20:00 | Tennessee Tech (W) v South Carolina (W) | W | 48-108 |
| WNCAAB | 2025/03/09 19:00 | Texas (W) v South Carolina (W) | W | 45-64 |
| WNCAAB | 2025/03/08 21:30 | Oklahoma (W) v South Carolina (W) | W | 75-93 |