Head to Head
| Mexico Liga MX Femenil | 2025/04/15 01:00 | Leon (W) v Santos Laguna (W) | W | 3-1 |
| Mexico Liga MX Femenil | 2024/10/18 23:00 | Santos Laguna (W) v Leon (W) | L | 5-0 |
| Mexico Liga MX Femenil | 2024/04/30 01:05 | Leon (W) v Santos Laguna (W) | W | 4-0 |
| Mexico Liga MX Femenil | 2023/10/21 03:10 | Santos Laguna (W) v Leon (W) | D | 2-2 |
| Mexico Liga MX Femenil | 2023/04/25 01:06 | Leon (W) v Santos Laguna (W) | D | 1-1 |
| Mexico Liga MX Femenil | 2022/08/02 00:00 | Santos Laguna (W) v Leon (W) | W | 1-2 |
| Mexico Liga MX Femenil | 2022/02/08 01:00 | Santos Laguna (W) v Leon (W) | W | 1-3 |
| Mexico Liga MX Femenil | 2021/08/24 00:00 | Leon (W) v Santos Laguna (W) | L | 1-6 |
Home History
| Mexico Liga MX Femenil | 2025/09/15 23:00 | Atletico San Luis (W) v Leon (W) | W | 0-3 |
| Mexico Liga MX Femenil | 2025/09/06 01:00 | Leon (W) v Chivas Guadalajara (W) | L | 1-2 |
| Mexico Liga MX Femenil | 2025/08/30 21:45 | Cruz Azul (W) v Leon (W) | W | 1-2 |
| Mexico Liga MX Femenil | 2025/08/26 01:00 | Puebla (W) v Leon (W) | W | 0-2 |
| Mexico Liga MX Femenil | 2025/08/19 01:00 | Leon (W) v Queretaro (W) | D | 2-2 |
| Mexico Liga MX Femenil | 2025/08/13 23:00 | Leon (W) v Juarez FC (W) | W | 3-2 |
| Mexico Liga MX Femenil | 2025/08/10 01:05 | Toluca (W) v Leon (W) | L | 1-0 |
| Mexico Liga MX Femenil | 2025/08/01 23:00 | Necaxa (W) v Leon (W) | D | 1-1 |
Away History
| Mexico Liga MX Femenil | 2025/09/16 01:00 | Santos Laguna (W) v Atlas (W) | L | 1-2 |
| Mexico Liga MX Femenil | 2025/09/08 01:00 | Tijuana (W) v Santos Laguna (W) | D | 1-1 |
| Mexico Liga MX Femenil | 2025/09/05 01:00 | Santos Laguna (W) v Necaxa (W) | L | 1-2 |
| Mexico Liga MX Femenil | 2025/09/02 02:00 | Santos Laguna (W) v Unam Pumas (W) | L | 3-5 |
| Mexico Liga MX Femenil | 2025/08/29 01:00 | Club America (W) v Santos Laguna (W) | L | 6-3 |
| Mexico Liga MX Femenil | 2025/08/17 03:00 | Monterrey (W) v Santos Laguna (W) | L | 3-1 |
| Mexico Liga MX Femenil | 2025/08/09 23:00 | Pachuca (W) v Santos Laguna (W) | L | 3-1 |
| Mexico Liga MX Femenil | 2025/08/05 01:00 | Santos Laguna (W) v Chivas Guadalajara (W) | W | 2-1 |
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