[3] TOR Maple Leafs 4-3 BUF Sabres [5] 2018-11-22 02:30
Stadium: KeyBank Center Round: 1
Home Manager: Phil Housley Away Manager: Mike Babcock
Head to Head
| NHL Pre-Season | 2018/09/22 23:00 | TOR Maple Leafs v BUF Sabres | W | 3-2 |
| NHL Pre-Season | 2018/09/21 23:30 | BUF Sabres v TOR Maple Leafs | W | 3-5 |
| NHL | 2018/04/02 23:00 | BUF Sabres v TOR Maple Leafs | W | 2-5 |
| NHL | 2018/03/26 23:00 | BUF Sabres v TOR Maple Leafs | L | 3-2 |
| NHL | 2018/03/15 23:00 | TOR Maple Leafs v BUF Sabres | W | 5-2 |
| NHL | 2018/03/06 00:30 | TOR Maple Leafs v BUF Sabres | L | 3-5 |
| NHL Pre-Season | 2017/09/23 23:00 | BUF Sabres v TOR Maple Leafs | W | 1-3 |
| NHL Pre-Season | 2017/09/22 23:30 | BUF Sabres v TOR Maple Leafs | W | 0-3 |
Home History
| NHL | 2018/11/22 00:00 | TOR Maple Leafs v CAR Hurricanes | L | 2-5 |
| NHL | 2018/11/20 00:00 | CLB Blue Jackets v TOR Maple Leafs | W | 2-4 |
| NHL | 2018/11/17 03:00 | TOR Maple Leafs v ANA Ducks | W | 2-1 |
| NHL | 2018/11/16 03:30 | TOR Maple Leafs v SJ Sharks | W | 5-3 |
| NHL | 2018/11/14 03:30 | TOR Maple Leafs v LA Kings | W | 5-1 |
| NHL | 2018/11/11 00:00 | TOR Maple Leafs v BOS Bruins | L | 1-5 |
| NHL | 2018/11/10 00:00 | NJ Devils v TOR Maple Leafs | W | 1-6 |
| NHL | 2018/11/07 00:00 | VGS Golden Knights v TOR Maple Leafs | W | 1-3 |
Away History
| NHL | 2018/11/22 00:30 | PHI Flyers v BUF Sabres | W | 2-5 |
| NHL | 2018/11/20 00:00 | BUF Sabres v PIT Penguins | W | 5-4 |
| NHL | 2018/11/17 23:00 | BUF Sabres v MIN Wild | W | 3-2 |
| NHL | 2018/11/17 01:00 | BUF Sabres v WPG Jets | W | 2-1 |
| NHL | 2018/11/14 00:30 | TB Lightning v BUF Sabres | W | 1-2 |
| NHL | 2018/11/10 18:00 | VAN Canucks v BUF Sabres | W | 3-4 |
| NHL | 2018/11/09 00:30 | BUF Sabres v MTL Canadiens | W | 6-5 |
| NHL | 2018/11/05 00:00 | BUF Sabres v NY Rangers | L | 1-3 |
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