| Uruguay Reserve League | 2024/05/13 18:00 | Defensor Sporting Reserves v Danubio Reserves | D | 1-1 |
| Uruguay Reserve League | 2023/05/15 13:00 | Danubio Reserves v Defensor Sporting Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/12/01 19:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-5 |
| Uruguay Reserve League | 2022/05/31 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 0-3 |
| Uruguay Reserve League | 2019/11/07 19:00 | Defensor Sporting Reserves v Danubio Reserves | L | 3-1 |
| Uruguay Reserve League | 2019/04/16 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 2-5 |
| Uruguay Reserve League | 2018/08/01 18:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-3 |
| Uruguay Reserve League | 2024/07/29 18:00 | Club Atletico Progreso Reserves v Danubio Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/07/22 18:00 | Danubio Reserves v Albion FC Reserves | L | 0-1 |
| Uruguay Reserve League | 2024/07/15 18:00 | Deportivo Maldonado Reserves v Danubio Reserves | D | 3-3 |
| Uruguay Reserve League | 2024/07/08 18:00 | Danubio Reserves v Boston River Reserves | L | 1-2 |
| Uruguay Reserve League | 2024/07/01 15:13 | Miramar Misiones Reserves v Danubio Reserves | W | 1-2 |
| Uruguay Reserve League | 2024/06/24 18:00 | Club Atletico Progreso Reserves v Danubio Reserves | L | 2-0 |
| Uruguay Reserve League | 2024/06/17 18:00 | Danubio Reserves v Miramar Misiones Reserves | W | 2-0 |
| Uruguay Reserve League | 2024/06/13 12:30 | Juventud De Las Piedras Reserves v Danubio Reserves | L | 4-1 |
| Uruguay Reserve League | 2024/07/29 18:00 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | W | 0-1 |
| Uruguay Reserve League | 2024/07/22 18:00 | Racing Club de Montevideo Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2024/07/15 18:00 | Defensor Sporting Reserves v Torque Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/07/08 18:00 | Penarol Reserves v Defensor Sporting Reserves | L | 2-0 |
| Uruguay Reserve League | 2024/07/01 18:00 | Defensor Sporting Reserves v Atletico Fenix Reserves | W | 2-0 |
| Uruguay Reserve League | 2024/06/24 12:00 | Defensor Sporting Reserves v Liverpool Montevideo Reserves | D | 2-2 |
| Uruguay Reserve League | 2024/06/17 18:00 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | L | 2-1 |
| Uruguay Reserve League | 2024/06/10 13:00 | Defensor Sporting Reserves v Albion FC Reserves | D | 1-1 |