Stadium: Credit Union 1 Arena
Home Manager: Luke Yaklich Away Manager: Darian DeVries
| CBI | 2022/03/21 17:00 | Drake v UNC Wilmington | L | 75-76 |
| CBI | 2022/03/19 16:00 | IPFW v Drake | W | 65-87 |
| NCAAB | 2022/03/06 19:00 | Loyola Chicago v Drake | L | 64-58 |
| NCAAB | 2022/03/05 23:00 | Drake v Missouri State | W | 79-78 |
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | W | 52-65 |
| NCAAB | 2022/02/26 21:00 | Southern Illinois v Drake | W | 60-62 |
| NCAAB | 2022/02/24 00:00 | Drake v Valparaiso | W | 71-65 |
| NCAAB | 2022/02/22 01:00 | Indiana State v Drake | W | 58-74 |
| NCAAB | 2022/03/04 00:00 | Illinois-Chicago v IPFW | L | 72-78 |
| NCAAB | 2022/03/02 01:00 | Illinois-Chicago v Wisc Milwaukee | W | 80-69 |
| NCAAB | 2022/02/27 01:00 | Wisc Milwaukee v Illinois-Chicago | W | 58-71 |
| NCAAB | 2022/02/25 01:00 | Wisc Green Bay v Illinois-Chicago | W | 77-81 |
| NCAAB | 2022/02/20 00:00 | Illinois-Chicago v Robert Morris | W | 96-88 |
| NCAAB | 2022/02/18 00:00 | Illinois-Chicago v Youngstown State | L | 79-88 |
| NCAAB | 2022/02/15 01:00 | IU Indianapolis v Illinois-Chicago | W | 54-57 |
| NCAAB | 2022/02/13 00:00 | Illinois-Chicago v IPFW | L | 66-73 |