Stadium: Younts Stadium Round: 1
| NCAAF | 2021/10/16 19:00 | Delta State v North Greenville Crusaders | W | 34-42 |
| NCAAF | 2019/09/28 23:00 | North Greenville Crusaders v Delta State | L | 9-34 |
| NCAAF | 2018/09/22 23:00 | Delta State v North Greenville Crusaders | W | 20-33 |
| NCAAF | 2021/11/13 17:00 | North Greenville Crusaders v Shorter | W | 56-0 |
| NCAAF | 2021/11/06 19:00 | Valdosta State v North Greenville Crusaders | L | 31-21 |
| NCAAF | 2021/10/30 16:00 | North Greenville Crusaders v West Alabama Tigers | L | 14-31 |
| NCAAF | 2021/10/23 22:00 | West Georgia v North Greenville Crusaders | L | 34-12 |
| NCAAF | 2021/10/16 19:00 | Delta State v North Greenville Crusaders | W | 34-42 |
| NCAAF | 2021/10/09 23:00 | North Greenville Crusaders v West Florida | L | 10-52 |
| NCAAF | 2021/10/02 19:00 | North Greenville Crusaders v Mississippi College Choctaws | L | 21-42 |
| NCAAF | 2021/09/25 17:00 | Erskine Flying Fleet v North Greenville Crusaders | W | 7-38 |
| NCAAF | 2021/11/13 18:00 | West Georgia v Delta State | L | 44-7 |
| NCAAF | 2021/11/06 19:00 | Delta State v Mississippi College Choctaws | W | 24-21 |
| NCAAF | 2021/10/30 19:00 | Delta State v Shorter | W | 14-13 |
| NCAAF | 2021/10/23 21:00 | West Alabama Tigers v Delta State | W | 30-35 |
| NCAAF | 2021/10/16 19:00 | Delta State v North Greenville Crusaders | L | 34-42 |
| NCAAF | 2021/10/09 23:00 | Valdosta State v Delta State | L | 55-0 |
| NCAAF | 2021/10/02 23:00 | Delta State v West Florida | L | 33-39 |
| NCAAF | 2021/09/25 19:00 | Jackson State v Delta State | L | 24-17 |