| England FA Premier Women | 2022/02/20 14:00 | Derby (W) v Loughborough Lightning (W) | D | 1-1 |
| England FA Premier Women | 2022/02/13 14:00 | Loughborough Lightning (W) v West Brom (W) | W | 2-1 |
| England FA Premier Women | 2022/01/30 14:00 | Loughborough Lightning (W) v Brighouse Town Women | W | 5-4 |
| England FA Premier Women | 2022/01/23 14:00 | Sheffield FC (W) v Loughborough Lightning (W) | D | 1-1 |
| England FA Premier Women | 2022/01/16 14:00 | Hull (W) v Loughborough Lightning (W) | W | 1-3 |
| England FA Premier Women | 2022/01/09 14:00 | AFC Fylde Women v Loughborough Lightning (W) | L | 2-0 |
| England FA Cup Women | 2021/12/12 13:00 | Huddersfield (W) v Loughborough Lightning (W) | L | 3-1 |
| England FA Cup Women | 2021/11/28 14:00 | Stevenage Women v Loughborough Lightning (W) | W | 0-2 |
| England FA Premier Women | 2022/02/06 14:00 | Hull (W) v Wolverhampton (W) | W | 0-5 |
| England FA Premier Women | 2022/01/26 19:45 | West Brom (W) v Wolverhampton (W) | W | 0-3 |
| England FA Premier Women | 2022/01/23 14:00 | Wolverhampton (W) v Derby (W) | W | 3-2 |
| England FA Cup Women | 2021/12/05 14:00 | Wolverhampton (W) v Nottm Forest (W) | L | 0-4 |
| England FA Cup Women | 2021/11/14 14:00 | Sporting Khalsa (W) v Wolverhampton (W) | W | 1-7 |
| England FA Premier Women | 2021/10/24 13:00 | Wolverhampton (W) v Burnley (W) | D | 2-2 |
| England FA Premier Women | 2021/10/07 18:45 | Stoke (W) v Wolverhampton (W) | W | 0-4 |
| England FA Premier Women | 2021/09/26 13:00 | Huddersfield (W) v Wolverhampton (W) | W | 2-3 |