Stadium: James H. Hilton Coliseum
Home Manager: Donte' Jackson Away Manager: T.J. Otzelberger
| NCAAB | 2021/03/13 02:30 | Grambling State v Prairie View | L | 63-74 |
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | W | 67-72 |
| NCAAB | 2021/03/07 02:00 | Alabama A&M v Grambling State | W | 72-80 |
| NCAAB | 2021/03/05 01:30 | Alabama State v Grambling State | W | 68-91 |
| NCAAB | 2021/03/02 01:30 | Grambling State v Mississippi Valley State | L | 63-67 |
| NCAAB | 2021/02/22 22:30 | Grambling State v Jackson State | L | 59-63 |
| NCAAB | 2021/02/13 21:30 | Texas Southern v Grambling State | L | 75-73 |
| NCAAB | 2021/02/09 01:30 | Grambling State v Alcorn State | W | 67-62 |
| NCAAB | 2021/03/11 02:30 | Iowa State v Oklahoma | L | 73-79 |
| NCAAB | 2021/03/06 22:00 | Iowa State v Kansas State | L | 56-61 |
| NCAAB | 2021/03/05 00:00 | Iowa State v Texas Tech | L | 54-81 |
| NCAAB | 2021/03/03 00:00 | Texas v Iowa State | L | 81-67 |
| NCAAB | 2021/02/27 23:00 | TCU v Iowa State | L | 76-72 |
| NCAAB | 2021/02/24 01:00 | Iowa State v Baylor Bears | L | 72-77 |
| NCAAB | 2021/02/20 23:00 | Oklahoma v Iowa State | L | 66-56 |
| NCAAB | 2021/02/16 21:00 | Iowa State v Oklahoma State | L | 58-76 |