Stadium: James H. Hilton Coliseum
Home Manager: David Kiefer Away Manager: T.J. Otzelberger
| NCAAB | 2021/11/28 18:30 | Western Michigan v SE Louisiana | L | 81-77 |
| NCAAB | 2021/11/27 21:30 | SE Louisiana v Florida Gulf Coast | L | 71-90 |
| NCAAB | 2021/11/26 21:30 | SE Louisiana v IPFW | L | 66-74 |
| NCAAB | 2021/11/23 00:00 | SE Louisiana v Ecclesia College | W | 121-79 |
| NCAAB | 2021/11/19 01:00 | SE Louisiana v SMU | L | 61-78 |
| NCAAB | 2021/11/14 19:00 | SE Louisiana v Paul Quinn College | W | 77-60 |
| NCAAB | 2021/11/13 01:00 | SE Louisiana v Southeastern Baptist Chargers | W | 128-58 |
| NCAAB | 2021/11/10 01:00 | SE Louisiana v Tulane | L | 67-70 |
| NCAAB | 2021/11/27 02:00 | Iowa State v Memphis | W | 78-59 |
| NCAAB | 2021/11/25 00:00 | Xavier v Iowa State | W | 70-82 |
| NCAAB | 2021/11/21 23:00 | Grambling State v Iowa State | W | 47-82 |
| NCAAB | 2021/11/17 01:00 | Alabama State v Iowa State | W | 60-68 |
| NCAAB | 2021/11/13 01:00 | Oregon State v Iowa State | W | 50-60 |
| NCAAB | 2021/11/10 01:00 | Kennesaw State v Iowa State | W | 73-84 |
| NCAAB | 2021/03/11 02:30 | Iowa State v Oklahoma | L | 73-79 |
| NCAAB | 2021/03/06 22:00 | Iowa State v Kansas State | L | 56-61 |