[44] Clemson 17-27 Pittsburgh [20] 2021-06-02 21:30
Stadium: Acrisure Stadium Round: 1
Home Manager: Pat Narduzzi Away Manager: Dabo Swinney
Head to Head
| NCAAF | 2020/11/28 20:30 | Pittsburgh v Clemson | W | 17-52 |
| NCAAF | 2018/12/02 01:00 | Pittsburgh v Clemson | W | 10-42 |
| NCAAF | 2016/11/12 20:30 | Pittsburgh v Clemson | L | 43-42 |
Home History
| NCAAF | 2021/01/02 01:00 | Ohio State v Clemson | L | 49-28 |
| NCAAF | 2020/12/19 21:00 | Clemson v Notre Dame | W | 34-10 |
| NCAAF | 2020/12/06 00:30 | Clemson v Virginia Tech | W | 45-10 |
| NCAAF | 2020/11/28 20:30 | Pittsburgh v Clemson | W | 17-52 |
| NCAAF | 2020/11/08 00:30 | Clemson v Notre Dame | L | 40-47 |
| NCAAF | 2020/10/31 16:00 | Boston College v Clemson | W | 28-34 |
| NCAAF | 2020/10/24 16:00 | Syracuse v Clemson | W | 21-47 |
| NCAAF | 2020/10/17 16:00 | Clemson v Georgia Tech | W | 73-7 |
Away History
| NCAAF | 2020/12/11 00:00 | Pittsburgh v Georgia Tech | W | 34-20 |
| NCAAF | 2020/11/28 20:30 | Pittsburgh v Clemson | L | 17-52 |
| NCAAF | 2020/11/21 21:00 | Virginia Tech v Pittsburgh | W | 14-47 |
| NCAAF | 2020/11/07 21:00 | Pittsburgh v Florida State | W | 41-17 |
| NCAAF | 2020/10/24 19:30 | Notre Dame v Pittsburgh | L | 45-3 |
| NCAAF | 2020/10/17 16:00 | Pittsburgh v Miami Florida | L | 19-31 |
| NCAAF | 2020/10/10 20:00 | Pittsburgh v Boston College | L | 30-31 |
| NCAAF | 2020/10/03 16:00 | NC State v Pittsburgh | L | 30-29 |
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