| Uruguay Reserve League | 2020/11/03 18:00 | Boston River Reserves v Defensor Sporting Reserves | L | 2-1 |
| Uruguay Reserve League | 2020/10/27 18:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | L | 0-1 |
| Uruguay Reserve League | 2020/10/06 18:00 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2020/09/15 18:00 | Defensor Sporting Reserves v Club Atletico Progreso Reserves | W | 1-0 |
| Uruguay Reserve League | 2020/09/01 18:00 | Defensor Sporting Reserves v Torque Reserves | W | 1-0 |
| Uruguay Reserve League | 2020/03/09 19:00 | Atletico River Plate Reserves v Defensor Sporting Reserves | D | 2-2 |
| Uruguay Reserve League | 2020/02/16 12:30 | Montevideo Wanderers Reserves v Defensor Sporting Reserves | W | 1-3 |
| Uruguay Reserve League | 2019/12/14 19:04 | Atletico River Plate Reserves v Defensor Sporting Reserves | D | 0-0 |