| Uruguay Reserve League | 2024/10/29 12:00 | Danubio Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2024/05/13 18:00 | Defensor Sporting Reserves v Danubio Reserves | D | 1-1 |
| Uruguay Reserve League | 2023/05/15 13:00 | Danubio Reserves v Defensor Sporting Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/12/01 19:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-5 |
| Uruguay Reserve League | 2022/05/31 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 0-3 |
| Uruguay Reserve League | 2019/11/07 19:00 | Defensor Sporting Reserves v Danubio Reserves | L | 3-1 |
| Uruguay Reserve League | 2019/04/16 18:00 | Danubio Reserves v Defensor Sporting Reserves | L | 2-5 |
| Uruguay Reserve League | 2018/08/01 18:00 | Defensor Sporting Reserves v Danubio Reserves | W | 0-3 |
| Uruguay Reserve League | 2025/04/14 19:00 | Danubio Reserves v Juventud De Las Piedras Reserves | L | 0-2 |
| Uruguay Reserve League | 2025/04/07 19:00 | Penarol Reserves v Danubio Reserves | L | 3-0 |
| Uruguay Reserve League | 2025/04/02 12:00 | Danubio Reserves v Torque Reserves | L | 0-3 |
| Uruguay Reserve League | 2025/03/24 19:00 | Boston River Reserves v Danubio Reserves | L | 2-1 |
| Uruguay Reserve League | 2025/03/20 19:00 | Danubio Reserves v La Luz Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/12/09 19:00 | Danubio Reserves v Club Atletico Progreso Reserves | W | 2-0 |
| Uruguay Reserve League | 2024/12/05 12:00 | Torque Reserves v Danubio Reserves | L | 2-0 |
| Uruguay Reserve League | 2024/12/02 12:00 | Miramar Misiones Reserves v Danubio Reserves | W | 1-2 |
| Uruguay Reserve League | 2025/04/17 18:00 | Montevideo Wanderers Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2025/04/14 16:30 | Defensor Sporting Reserves v Club Oriental Reserves | W | 3-1 |
| Uruguay Reserve League | 2025/04/08 12:30 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | D | 0-0 |
| Uruguay Reserve League | 2025/03/31 12:00 | Defensor Sporting Reserves v Club Atletico Progreso Reserves | D | 3-3 |
| Uruguay Reserve League | 2025/03/24 19:00 | Racing Club de Montevideo Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2025/03/17 12:30 | Defensor Sporting Reserves v Juventud De Las Piedras Reserves | L | 1-2 |
| Uruguay Reserve League | 2025/03/10 19:30 | Penarol Reserves v Defensor Sporting Reserves | W | 0-1 |
| Uruguay Reserve League | 2025/02/28 12:00 | Defensor Sporting Reserves v Torque Reserves | L | 2-3 |